How Efficient Are The Oral Anticoagulants Over Warfarin Assignment

How Efficient Are The Oral Anticoagulants Over Warfarin - Assignment Example On the other hand, the action new oral anticoagulants in the body; dabigatran, in this case, can be reversed using hemodialysis. This method works to remove dabigatran from the body in 3 hours hence it can be used to treat dabigatran toxicity. Dabigatran, rivaroxaban, and apixaban are eliminated from the body through the renal system. Before their administration, clinicians are advised to diagnose and ascertain the patient's creatinine clearance using the Cockcroft-Gault formula. This will help in determining the dosage requirement for various patients. In warfarin administration, there is no agreed mechanism of administering the dosages to patients. The drug has been in use for 60 years yet clinicians do not have a clear basis for determining the right amount of the drug to be administered to patients. Various factors that inhibit the function of warfarin have been identified and they vary from patient to patient. This makes it difficult for clinicians to ascertain the correct dosag e for various patients. This is one of the reasons that make warfarin less effective and more dangerous compared to the new oral anticoagulants. All the above arguments present evidence against the use of warfarin. It limitations has made it ineffective for clinical use but despite this, it is still used by clinicians all over the world since there is no established cure for the conditions it treats. New oral anticoagulants, on the other hand, have been found to have lesser flaws and are more effective in treating patients with nonvalvular AF.